Sunday, December 31, 2006

Gene Therapy for Malicious Bacteria

An interesting concept on treating bacterial infections, without encouraging drug-resistant varieties to evolve, is adapting gene therapy to disarm the toxin releasing bacteria by replacing the "bad" genes with harmless gobbledy-gook. Genetically modified e. coli will be the carriers of the harmless genes, so that as the harmful bacteria multiply, the newer bacteria will no longer be able to produce the toxins. I would have liked to see more on how the e. coli actually introduce the displacins, but we know that bacteria love exchanging plasmids, it's only when the plasmids are harmful to the bacteria do they begin releasing their toxins, such as the immune response from our white cells, to destroy those plasmids. But with knowing the specific code of the bacteria, scientists are able to mimic the harmful bacteria's own plasmids, so that they can stroll right through the toxin storm. Pretty cool stuff. I'm sure the Euros will be okay with GM e. coli, just as long as it's not rice.

Update: Someone wants credit for taking more biology classes than I did in school contributing to the post. Thanks bro.

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